CF10 ODBC Socket Error - TCP/IP error, connection refused

Trying to define ODBC datasource for Excel.  Getting foloowing error:

Connection verification failed for data source: ABCDEF

java.sql.SQLException: [Macromedia][SequeLink JDBC Driver]TCP/IP error, connection refused.

The root cause was that: java.sql.SQLException: [Macromedia][SequeLink JDBC Driver]TCP/IP error, connection refused.

Also, getting same errot for a Microsoft Access datasource.

Any suggestions?  Thanks in advance.