CF11 on Windows 2012 Multiple Domains Issue - will load directory, but not direct CFMs

I have a strange issue where I have two web sites:

D:\inetpub\wwwroot\

and

D:\inetpub\webapps\

which are bound to different domains.

Everything on the default (wwwroot) works fine with ColdFusion.

However, on the "webapps" site it will ONLY load CFM files if I call them implicitly as a directory.

For example:

http://my.site.com/

loads the index.cfm just fine, however:

http://my.site.com/index.cfm

always returns a 404 error.  Is there some sort of mapping or permission I need to set to make this work?

I checked wsconfig and it is set for All IIS websites.  I also made sure the IIS_IUSRS permission is set on it.

Anyone seen this?  I appreciate any advice.

Thanks!

Dan